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Angebot 233 von 383 vom 02.03.2023, 12:34

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Cha­rité Uni­ver­si­täts­me­di­zin Ber­lin - Chirur­gis­che Klinik - Exper­i­mentelle Chirur­gie

The Molecu­lar Car­ci­no­gen­esis Lab at Char­ité – Uni­versitätsmed­izin Ber­lin is offer­ing a 3-year full-pos­i­tion (E13, 90%, 35h/Wo) for a com­pu­ta­tional bio­lo­gist aim­ing for an aca­demic degree.

Web­site: https://www.experimental-surgery.de/Projects/molecular_carcinogenesis/

PhD Stu­dent (f/m/d) in Bioin­form­at­ics at Char­ité – Uni­versitätsmed­izin Ber­lin

Working field:

Are you inter­ested to work on cut­ting-edge can­cer research, and invest­ig­at­ing com­plex-chro­mo­somal and other gen­omic phe­nom­ena in human car­cinoma cells ? We are look­ing to hire a com­pu­ta­tional bio­lo­gist to work on com­plex gen­ome ana­lyses (single-cell ana­lyses, whole gen­ome ana­lyses) to detect, annot­ate and re-con­struct cir­cu­lar DNA for bet­ter under­stand­ing of the molecu­lar tra­ject­ory of can­cer devel­op­ment. We are a young, dynamic team with par­tic­u­lar interest on molecu­lar car­ci­no­gen­esis in pan­cre­atic adeno­car­cinoma. As clini­cian sci­ent­ist (Ber­lin Insti­tute of Health), we provide motiv­a­tion and high com­mit­ment in super­vi­sion in areas around exper­i­mental onco­logy and sur­gery. Fun­ded by the Else Kröner Fresenius Stif­tung (EKFS), the pos­i­tion allows the applic­ant to pur­sue an aca­demic qual­i­fic­a­tion, while col­lab­or­at­ing and net­work­ing with inter­na­tional experts on extra­chromo­somal cir­cu­lar DNA (Pro­fessor Dr. A. Henssen, Max-Del­brück Centre / Char­ité Ber­lin) and pan­cre­atic car­ci­no­gen­esis (Pro­fessor Laura Wood, Johns Hop­kins Uni­versity, Bal­timore/US).

Requirements:

  • Com­pleted stud­ies (Mas­ter or equi­val­ent) in bioin­form­at­ics or med­ical inform­at­ics.
  • Ver­sat­ile with R pro­gram­ming lan­guage (man­dat­ory); pro­gram­ming skills in Python are a plus.
  • Exper­i­ence/know­ledge in areas of gen­ome/tran­scip­tome ana­lysis and bioin­form­atic algorithms (e.g. cluster meth­ods)
  • Very good lan­guage skills in Eng­lish. Good lan­guage skills in Ger­man is a plus.
  • High-motiv­a­tion and abil­ity to work effect­ively both, inde­pend­ently as well as in teams.
  • Strong verbal and writ­ten com­mu­nic­a­tion skills.
  • Alto­gether good ana­lyt­ical skills to address com­plex patho­bi­o­lo­gical research ques­tions.
  • Exper­i­ence with Slurm HPC Sched­uler or sim­ilar is a plus

What we offer:

  • Bioin­form­atic pro­cessing of gen­ome-wide sequen­cing data (WGS, Nan­o­pore, RNASeq, Single Cell Seq).
  • Applic­a­tion of innov­at­ive tool for recon­struc­tion of com­plex gen­omic aber­ra­tions (Amp­l­icon Archi­tect).
  • Present­a­tion and pub­lic­a­tion of research res­ults.
  • Inter­ac­tion and close col­lab­or­a­tion with research part­ners in Ger­many and world­wide.

How to apply:

Please send a brief cover let­ter and CV via email by March 31st to Dr. med. Mat­thäus Felsen­tein (matthaeus.felsenstein@charite.de). If you have fur­ther ques­tions, please do not hes­it­ate to con­tact me.