Conducting animal experiments. The aim is to establish orthotopic pancreatic tumours in mice. The job holder will treat the animals with oncolytic viruses or a combination therapy consisting of oncolytic viruses, FAK inhibitors and checkpoint inhibitors. The success of the therapy will be verified in vivo using bioluminescence measurement. Furthermore, the position holder will produce the oncolytic viruses and verify their functionality in vitro. He/she will examine samples taken from the animals using molecular biological (PCR, etc.) and virological techniques (plaque assays, etc.). He/she is responsible for planning, conducting and evaluating animal experiments, summarising the data obtained, and writing scientific manuscripts and conference papers. In addition, he/she is responsible for communicating with authorities and drafting amendment applications for animal experiments.

• successfully completed scientific university degree (Master's, Diploma or equivalent) in biotechnology, biology or biochemistry
• several years of solid experience in conducting animal experiments
• experience working with in vivo bioluminescence measurements
• solid knowledge of biochemistry, molecular biology, virology (several years of experience)
• relevant practical experience in working with viruses (S2 organisms)
• relevant experience in genetic engineering work
• German language proficiency at least at the C1 level (certificate)
• willingness to work on weekends
• generation of orthotopic pancreatic tumours in mice (desirable)
• knowledge of preparing animal testing applications and amendment requests for animal testing (desirable)
• knowledge of preparing genetic engineering applications (desirable)

Please send your application with the usual documents (curriculum vitae, overview of grades/transcripts and letter of application, summarized in a PDF document, max. 5 MB) by e-mail to Dr. Henry Fechner at info@angewbiochem.tu-berlin.de, quoting the reference number.

By submitting your application via email you consent to having your data electronically processed and saved. Please note that we do not provide a guarantee for the protection of your personal data when submitted as unprotected file. Please find our data protection notice acc. DSGVO (General Data Protection Regulation) at the TU staff department homepage: https://www.abt2-t.tu-berlin.de/menue/themen_a_z/datenschutzerklaerung/.

To ensure equal opportunities between women and men, applications by women with the required qualifications are explicitly desired. Qualified individuals with disabilities will be favored. The TU Berlin values the diversity of its members and is committed to the goals of equal opportunities. Applications from people of all nationalities and with a migration background are very welcome.